• DNA Targeting by a CRISPR-Cas Complex
    • DNA Targeting by a CRISPR-Cas Complex
    • DNA Targeting by a CRISPR-Cas Complex
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    •   Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex Electron-microscopy images reveal how a CRISPR system marks specific DNA sequences for destruction. Microbes use CRISPR as a defense system to fend off viruses and other invaders, and geneticists have harnessed it to alter DNA sequences in a process called gene editing. We used cryo-electron microscopy…