Protein Secondary Structure Determination by Constrained Single-Particle Cryo-Electron Tomography We propose a hybrid strategy, constrained single-particle tomography (CSPT), that combines the advantages of cryo-electron tomography and subvolume averaging with those of traditional single-particle reconstruction and projection matching refinement. Its key components are the effective manipulation of images from tomographic tilt series to successfully extract high-resolution information and correct for…
A collaborative framework for 3D alignment and classification of heterogeneous subvolumes in cryo-electron tomography Journal of Structural Biology 181(2):116-27, 2013.
An Energy-based Three-dimensional Segmentation Approach for the Quantitative Interpretation of Electron Tomograms IEEE Trans Image Process,14(9):1314-23, 2005.
