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- Single-Particle Cryo-Electron Microscopy: Mathematical Theory, Computational Challenges, and Opportunities This issue of IEEE Signal Processing Magazine includes three feature articles covering cooperative wireless caching, atomic norm minimization for super- resolution, and single-particle cryo-electron microscopy (the latter on which this issue’s cover design is based). Signal Processing Magazine, 37(2), March 2020.
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- Cryo-EM in drug discovery: achievements, limitations and prospects Recent technological advances with cryo-electron microscopy (cryo-EM) — a biophysical technique that can be used to determine the structure of biological macromolecules and assemblies — have raised hopes that it might soon become an important tool for drug discovery, particularly for 'intractable' targets that are still not accessible to analysis by…
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- Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase Molecular Pharmacology, 89(6), 2016
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- The End of 'blob-ology': Single-Particle Cryo-EM is Now Being Used to Solve Macromolecular Structures at High Resolution Nature Methods, 13(1), 2015.
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- Prefusion Structure of Trimeric HIV-1 Envelope Glycoprotein Determined by Cryo-Electron Microscopy HIV-1 Env transitions from a closed to an open state upon binding to its cellular receptor. Single-particle cryo-EM analysis now reveals the closed state of the HIV-1 Env trimer at ~6-Å resolution, featuring three gp41 helices at the center of the trimer depicted here by the tri-fold organization…
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- A Collaborative Framework for 3D Alignment and Classification of Heterogeneous Subvolumes in Cryo-Electron Tomography Journal of Structural Biology, 181(2), 2013.
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- Cryo-Electron Microscopy – A Primer for the Non-Microscopist From molecules to viruses and cells: Bridging the gap with 3D electron microscopy FEBS Journal, 280(1), 2013.
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- Is it Ever Too Early? IAVIReport, 16(3), 2012.
